Sumatriptan and cerebral perfusion in healthy volunteers
| Autor: | M Critchley, C Thomson, AK Scott, AJ Pilgrim, S Grimes, K Ng, Alasdair Breckenridge |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Indoles Migraine Disorders Hemodynamics Healthy volunteers medicine Humans Vasoconstrictor Agents Pharmacology (medical) Cerebral perfusion pressure Adverse effect Volunteer Pharmacology Sulfonamides Sumatriptan business.industry Middle Aged musculoskeletal system Cerebrovascular Circulation Blood pressure Anesthesia cardiovascular system business Research Article medicine.drug |
| Zdroj: | British Journal of Clinical Pharmacology. 33:401-404 |
| ISSN: | 0306-5251 |
| DOI: | 10.1111/j.1365-2125.1992.tb04058.x |
| Popis: | 1. The effect of sumatriptan on regional cerebral perfusion was studied in healthy volunteers. 2. Intravenous sumatriptan (2 mg) had no detectable effect on regional cerebral perfusion as measured using a SPECT system with 99technetiumm labelled hexemethylpropyleneamineoxime. 3. Sumatriptan had no effect on pulse, blood pressure or ECG indices. 4. All six volunteers experienced minor adverse effects during the intravenous infusion. |
| Databáze: | OpenAIRE |
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