Severe Cystic Echinococcosis-Associated Immune Thrombocytopenic Purpura: A Case Report
| Autor: | Hans Knecht, Jean Sebastien Pelletier, Sami Morin-Ben Abdallah, Marc Bienz, Stephen Caplan, Christina Greenaway |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Case Report Gastroenterology Albendazole 03 medical and health sciences Refractory Prednisone immune system diseases Internal medicine hemic and lymphatic diseases medicine Hydatid cysts Dexamethasone biology business.industry 030108 mycology & parasitology medicine.disease biology.organism_classification Thrombocytopenic purpura Echinococcosis Thrombocytopenia Echinococcus Parasite 030104 developmental biology Immune thrombocytopenic purpura Hepatic Cyst business medicine.drug |
| Zdroj: | Journal of Hematology |
| ISSN: | 1927-1220 1927-1212 |
| Popis: | We present a case of immune thrombocytopenic purpura (ITP), which leads to the diagnosis of severe cystic echinococcosis. Our patient presented with platelets of 5 × 109/L, and investigations uncovered multiple large echinococcal hepatic cysts, the largest of which measured 19.4 × 15 × 12 cm, and peritoneal implants. While initially refractory to prednisone and immunoglobulins, the ITP responded to dexamethasone. The echinococcosis was treated with albendazole followed by surgical resection of all lesions. Our patient's disease course has evolved favorable since his initial treatment with an isolated episode of recurrent thrombocytopenia 2 years later, and has remained in remission for the past 2 years. While a causal association between echinococcosis and ITP cannot be confirmed, this case is a reminder of the importance of remaining inquisitive for atypical potential triggers of ITP. We also present a review of the limited literature on the association of parasitic infections and ITP. |
| Databáze: | OpenAIRE |
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