Chlamyweb Study II: a randomised controlled trial (RCT) of an online offer of home-based Chlamydia trachomatis sampling in France
| Autor: | Cécile Bébéar, Pierre Arwidson, Delphine Kersaudy-Rahib, Chloé Leroy, Laura March, Bertille de Barbeyrac, Nathalie Lydié |
|---|---|
| Přispěvatelé: | Sexual Health Unit, Institut de Santé Publique, d'Epidémiologie et de Développement (ISPED), Institut National de la Santé et de la Recherche Médicale (Inserm)-Université de Bordeaux-Institut National de la Santé et de la Recherche Médicale (Inserm)-Université de Bordeaux, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, Institut National de la Recherche Agronomique (INRA), Université de Bordeaux (UB) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Pediatrics [SDV]Life Sciences [q-bio] sexual health chlamydia trachomatis Context (language use) Dermatology medicine.disease_cause law.invention Health serv research 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Intervention (counseling) Internal medicine medicine maladie sexuellement transmissible 030212 general & internal medicine Young adult Reproductive health 030505 public health Chlamydia business.industry screening Intervention studies medicine.disease 3. Good health Infectious Diseases Relative risk 0305 other medical science Chlamydia trachomatis business |
| Zdroj: | Sexually Transmitted Infections Sexually Transmitted Infections, BMJ Publishing Group, 2017, 93 (3), pp.188-195. ⟨10.1136/sextrans-2015-052510⟩ |
| ISSN: | 1368-4973 1472-3263 |
| Popis: | Background The number of cases of Chlamydia trachomatis (Ct) diagnosed has increased in the past 15 years in France as well as in other European countries. This paper reports a randomised controlled trial (RCT) to evaluate whether the offer of home-based testing over the internet increased the number of young people tested for chlamydia compared with the current testing strategy and to estimate the number and risks factors of the infected population. This RCT took place as an element of the Chlamyweb Study—a study aiming to evaluate an intervention (the Chlamyweb Intervention) involving the offer of a free self-sampling kit online to sexually active men and women aged 18–24 years in France. Methods Participants in the Chlamyweb RCT (n=11 075) received either an offer of a free self-sampling kit (intervention group) or were invited to be screened in primary care settings (control group). Risks ratios were used to compare screening rates between the intervention and control groups. Risk factors were analysed for infected people in the intervention group. Results The screening frequency was about three times higher among young people who received a self-sampling kit than those who only received a tailored recommendation to be screened (29.2% vs 8.7%). Although rates of screening among men were lower than among women (23.9% vs 33.9%), the intervention effect was greater among men (adjusted risk ratios (aRR)=4.55 vs aRR=2.94). Ct positivity (6.8%) was similar to that observed in STI clinics. It was higher in women (8.3%) than in men (4.4%). Conclusions These results invite us to consider the establishment of a large home-based screening programme, although additional studies including economic assessments are needed to evaluate the most appropriate combination of strategies in the French context. Trial registraion number AFFSAPS n° IDRCB 0211-A01000-41; Results. |
| Databáze: | OpenAIRE |
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