Preclinical disease and preventive strategies in IBD
| Autor: | B Morão, Joana Torres |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Population Disease Disease pathogenesis 030226 pharmacology & pharmacy Inflammatory bowel disease 03 medical and health sciences 0302 clinical medicine Immune system Drug Discovery medicine Animals Humans Intensive care medicine education Pharmacology education.field_of_study business.industry Inflammatory Bowel Diseases medicine.disease Primary Prevention 030104 developmental biology Preclinical phase Clinical diagnosis Disease prevention business Biomarkers |
| Zdroj: | Current Opinion in Pharmacology. 55:110-115 |
| ISSN: | 1471-4892 |
| Popis: | There is growing evidence that inflammatory bowel disease has a preclinical phase that precedes disease symptoms, during which immune system activation has already occurred and inflammatory pathways have been primed, setting the stage for disease to expand and leading up to clinical diagnosis. Gaining insight to this pre-diagnosis period could improve our knowledge about disease pathogenesis and potentially result in the detection of biomarkers that could predict disease development. The ultimate goal of such research is to identify a population at risk for developing IBD, so preventive strategies could be implemented and disease prevention be achieved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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