Hypofractionated radiotherapy for elderly breast cancer patients: from early stages disease to local palliation for unresectable disease
| Autor: | Vimoj Nair, Jean-Michel Caudrelier |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Oncology
Hypofractionated Radiotherapy Cancer Research medicine.medical_specialty partial breast radiation hypofractionation business.industry Unresectable disease Review Article Disease medicine.disease re-irradiation Regimen Breast cancer Locally advanced disease Internal medicine palliative radiation therapy medicine Radiotherapy dose Radiology Nuclear Medicine and imaging Breast disease Elderly breast cancer skin and connective tissue diseases business |
| Zdroj: | Translational Cancer Research |
| ISSN: | 2219-6803 2218-676X |
| DOI: | 10.21037/tcr.2019.09.20 |
| Popis: | There is a lack of clear guidelines on optimal radiotherapy dose regimen for elderly breast cancer patients. This review summarizes the current evidence on role of hypofractionated radiotherapy in elderly breast cancer. Also, suggestions have been provided on the best fractionation approaches based on current evidence. Hypofractionated radiotherapy is feasible and well tolerated in elderly breast cancer patients with both early and locally advanced disease. Ultra-hypofractionated regimen seem appropriate for palliation of unresectable primary breast disease and could become a safe approach for adjuvant treatments. Hypofractionated radiotherapy should be considered for treatment of elderly breast cancer for curative intent, as well as for palliation. |
| Databáze: | OpenAIRE |
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