Trace lithium is inversely associated with male suicide after adjustment of climatic factors
| Autor: | Takeshi Terao, Kentaro Kohno, Yoshinori Mizokami, Nobuyoshi Ishii, Masayuki Kanehisa, Sanshi Tanabe, Shinya Matusda, Shouhei Takeuchi, Yoshiki Kuroda, Ippei Shiotsuki, Koji Hatano, Noboru Iwata |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Gerontology
Male Lithium (medication) Injury control Accident prevention Climate Population Poison control Lithium Suicide prevention 03 medical and health sciences 0302 clinical medicine Sex Factors medicine Humans education education.field_of_study business.industry Drinking Water Rain fall Temperature 030227 psychiatry Psychiatry and Mental health Clinical Psychology Suicide Female Seasons business 030217 neurology & neurosurgery Demography medicine.drug |
| Zdroj: | Journal of affective disorders. 189 |
| ISSN: | 1573-2517 |
| Popis: | Background Previously, we showed the inverse association between lithium in drinking water and male suicide in Kyushu Island. The narrow variation in meteorological factors of Kyushu Island and a considerable amount of evidence regarding the role of the factors on suicide provoked the necessities of adjusting the association by the wide variation in sunshine, temperature, rain fall, and snow fall. Methods To keep the wide variation in meteorological factors, we combined the data of Kyushu (the southernmost city is Itoman, 26°) and Hokkaido (the northernmost city is Wakkanai, 45°). Multiple regression analyses were used to predict suicide SMRs (total, male and female) by lithium levels in drinking water and meteorological factors. Results After adjustment of meteorological factors, lithium levels were significantly and inversely associated with male suicide SMRs, but not with total or female suicide SMRs, across the 153 cities of Hokkaido and Kyushu Islands. Moreover, annual total sunshine and annual mean temperature were significantly and inversely associated with male suicide SMRs whereas annual total rainfall was significantly and directly associated with male suicide SMRs. Limitations The limitations of the present study include the lack of data relevant to lithium levels in food and the proportion of the population who drank tap water and their consumption habits. Conclusions The present findings suggest that trace lithium is inversely associated with male but not female suicide after adjustment of meteorological factors. |
| Databáze: | OpenAIRE |
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