Atypical and disparate presentations of laryngeal sarcoidosis
Autor: | Michael J. Pitman, Ross M. Mayerhoff |
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Rok vydání: | 2010 |
Předmět: |
Larynx
Adult medicine.medical_specialty Systemic disease Sarcoidosis Laryngeal Diseases 03 medical and health sciences Young Adult 0302 clinical medicine medicine Humans 030223 otorhinolaryngology Child Paresis Retrospective Studies business.industry Retrospective cohort study General Medicine Middle Aged medicine.disease Dysphagia Dermatology Surgery medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis Granuloma Female Steroids medicine.symptom business |
Zdroj: | The Annals of otology, rhinology, and laryngology. 119(10) |
ISSN: | 0003-4894 |
Popis: | Sarcoidosis is a multisystem chronic granulomatous disease of unknown cause that typically affects patients between 20 and 40 years of age. Laryngeal involvement most frequently involves the supraglottis and presents with dyspnea. We present a retrospective review of 4 patients with previously undiagnosed sarcoidosis who presented with atypical signs and symptoms of sarcoidosis: dysphonia with isolated vocal fold involvement; cough and globus pharyngeus; pediatric sarcoidosis; and severe bilateral vocal fold paresis and dysphagia. Our aim is to highlight disparate presentations of laryngeal sarcoidosis, as well as the treatment options. Laryngeal sarcoidosis may present with atypical signs and symptoms and occasionally presents in pediatric patients. A high degree of suspicion is necessary for a correct diagnosis in these patients. Early diagnosis and proper management of laryngeal sarcoidosis is important, as the symptoms are debilitating and possibly life-threatening. Treatment may consist of local and systemic chemotherapy, and adjunctive procedures. |
Databáze: | OpenAIRE |
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