Severe aortic regurgitation in RF positive polyarticular JIA
| Autor: | Willem F. Lems, J Lindeman, B A C Dijkmans, Irene E. M. Bultink, R. M. Van Soesbergen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty Letter Anti-nuclear antibody business.industry Immunology Arthritis medicine.disease General Biochemistry Genetics and Molecular Biology Surgery Rheumatology Sulfasalazine Ankylosis Immunology and Allergy Medicine Rheumatoid factor Medical history Polyarthritis business Muscle contracture medicine.drug |
| Popis: | An 18 year old girl of Moroccan origin with a clear medical history was transferred to the Netherlands in February 1989 because of a two year history of untreated polyarthritis. The disease had pursued a rapidly destructive course, resulting in contractures and ankylosis of hips, knees, shoulders, and elbows and small joint deformation. A diagnosis of juvenile idiopathic arthritis (JIA) polyarticular type, functional class IV was made. No nodules were present. Laboratory analysis at that time showed borderline positive serum rheumatoid factor (RF) 30 IE/ml. Tests for antinuclear antibodies and HLA-B27 were negative. Treatment was started with intensive physiotherapy and intramuscular gold, the latter being replaced by sulfasalazine because of proteinuria. In 1990 she was treated for a unilateral uveitis. In 1992 her right elbow was replaced. Until 1993 cardiac examination showed no murmurs and chest roentgenogram … |
| Databáze: | OpenAIRE |
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