Additional file 3 of TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection

Autor: Aldrich, Amy L., Heim, Cortney E., Shi, Wen, Fallet, Rachel W., Duan, Bin, Kielian, Tammy
Rok vydání: 2020
DOI: 10.6084/m9.figshare.12127665.v1
Popis: Additional file 3: NLRP3 and its adaptor ASC do not dramatically affect S. aureus craniotomy infection. WT, NLRP3 KO, and ASC KO mice (n=5 mice/group) were sacrificed at days 3, 7, or 14 following S. aureus craniotomy infection, whereupon bacterial burden in the galea, brain, and bone flap was quantified. Results were analyzed by One-way ANOVA with Tukey’s multiple comparison test (*, p < 0.05; **, p < 0.01).
Databáze: OpenAIRE