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Calotropis gigantea is a milkweed, gigantic Swallow wort. Calotropis species is a common wasteland weed and are widely used as alternative therapeutic tool for the prevention or treatment of many diseases. This study was designed to extract n- heptane, ethyl acetate, ethanol and aqueous extracts from leaves and stems by Soxhlet method. To screen the presence of the bioactive compounds, was identified by phytochemical screening assays. To evaluate total antioxidant activity by various radical scavenging assays and to investigate the antimicrobial assays and bioassays such as mosquitocidal activity, antibiofilm activity, antiangiogenic assay and cytotoxicity – MTT Assay were performed. This study showed presence of various phytochemicals and the extracts were significantly showed more effective free radical scavenging activity. Out of all the extracts, ethyl acetate extracts of leaves and stems showed good efficiency in antimicrobial activity, mosquitocidal activity, antibiofilm activity, antiangiogenic assay and cytotoxicity assay showed potentially high values on ethyl acetate extract of leaves and stems. From the observed results Calotropis gigantea (Linn.) R.Br leaves and stems can be used as potentially active for various clinical purposes. |
