A genetic map of the mouse with 4,006 simple sequence length polymorphisms

Autor:	Joyce C. Miller, Andre Marquis, Alec W. Gross, William F. Dietrich, Deborah Damron, David C. Page, Eric S. Lander, Lincoln Stein, Robert G. Steen, Mark Merchant, Nathan Goodman, Robert Dredge, Diane C. Joyce, Robert Nahf, Michael Wessel
Rok vydání:	1994
Předmět:	Genetic Markers Male Genetics Genome Polymorphism Genetic X Chromosome Chromosome Mapping Chromosome Biology Mice Centimorgan Gene mapping Genetic marker Animals Microsatellite Female Simple sequence length polymorphism Crosses Genetic X chromosome
Zdroj:	Nature Genetics. 7:220-245
ISSN:	1546-1718 1061-4036
DOI:	10.1038/ng0694supp-220
Popis:	We have constructed a genetic map of the mouse genome containing 4,006 simple sequence length polymorphisms (SSLPs). The map provides an average spacing of 0.35 centiMorgans (cM) between markers, corresponding to about 750 kb. Approximately 90% of the genome lies within 1.1 cM of a marker and 99% lies within 2.2 cM. The markers have an average polymorphism rate of 50% in crosses between laboratory strains. The markers are distributed in a relatively uniform fashion across the genome, although some deviations from randomness can be detected. In particular, there is a significant underrepresentation of markers on the X chromosome. This map represents the two-thirds point toward our goal of developing a mouse genetic map containing 6,000 SSLPs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d6a98a21ce51375e597a2a7b50712e https://doi.org/10.1038/ng0694supp-220 Zobrazit plný text záznamu