Intestinal parasitic infections in HIV/AIDS patients presenting with diarrhoea in Jakarta, Indonesia
Autor: | Agnes Kurniawan, Sri W. Dwintasari, Ika Puspa Sari, Teguh Haryono Karyadi, Huw V. Smith, Evy Yunihastuti, Samsuridjal Djauzi |
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Rok vydání: | 2009 |
Předmět: |
Adult
Diarrhea Male AIDS-Related Opportunistic Infections Population Cryptosporidium HIV Infections Cyclospora cayetanensis Microbiology Cohort Studies Young Adult Coccidia parasitic diseases medicine Humans Blastocystis hominis Intestinal Diseases Parasitic education education.field_of_study Blastocystis biology Giardia Incidence Public Health Environmental and Occupational Health General Medicine biology.organism_classification medicine.disease CD4 Lymphocyte Count Cyclospora Cross-Sectional Studies Infectious Diseases Indonesia Coinfection Parasitology medicine.symptom |
Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 103:892-898 |
ISSN: | 0035-9203 |
Popis: | We investigated the occurrence of intestinal parasites in Indonesian HIV/AIDS patients with chronic diarrhoea prior to administering antiretroviral therapy. The influence of age, CD4(+) cell count and season on parasite occurrence was also studied. In total, 318 unconcentrated stool samples were analysed using Lugol's iodine and modified acid fast staining to detect intestinal coccidia. Most samples (94.5%) were from males aged 21-40 years with CD4(+) counts < or = 50 cells/mm(3). Parasites were found in 84.3% of samples (single species infections, 71.4%; polyparasitism, 12.9%), with protozoan pathogens occurring most commonly. Cryptosporidium (4.9%), Cyclospora cayetanensis (4.5%) and Giardia duodenalis (1.9%) were the most frequent single infections, but Blastocystis hominis (72.4%) was the most commonly occurring protist. Cryptosporidium and C. cayetanensis occurred in 11.9% and 7.8% of all (single and mixed) infections. The most common co-infection was with B. hominis and Cryptosporidium (6.3%). Intestinal protozoan pathogens were detected more frequently in cases with CD4(+) counts < or = 200/mm(3). No seasonal influence was determined for Cryptosporidium, C. cayetanensis or B. hominis, but gross seasonal disturbances may have influenced our findings. Intestinal parasites should be looked for routinely in this group of individuals and should be treated to reduce complications and the likelihood of transmission. |
Databáze: | OpenAIRE |
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