Metabolism of Adrenocortical Hormone in Surgical Stress

Autor: SHIGENOBU KUDOH, TOMIHISA FUNYU, YASUO SHIRAIWA, MIZUO TAMURA, YURIKO TERAYAMA, KAZUO NIGAWARA
Rok vydání: 1973
Předmět:
Zdroj: The Tohoku Journal of Experimental Medicine. 110:139-148
ISSN: 1349-3329
0040-8727
DOI: 10.1620/tjem.110.139
Popis: Urinary 17-OHCS (total, free and individual fractions) were determined using TLC in patients who underwent various operations, and the following results were obtained. When control urine was collected on the day before operation, the values were high. Severe urinary infection, high fever, and irradiation treatment influenced the adrenocortical function. The variation of urinary free 17-OHCS corresponded with the variation of total 17-OHCS in major operations. With the progress of severity of surgical stress, increase in individual fractions was seen in the following order; THE, THE and compound F. Also there existed the limit of excretion for individual fractions except comp. F; camp. E up to about 1.0 mg/day, THE 7.0 to 10.0 mg/day, THE about 10.0 mg/day. The order of decrease after the maximum response was exactly opposite to that of increment.
Databáze: OpenAIRE