Forensic toxicological study on adipocere formation in submerged cadavers of female albino rats intoxicated with cadmium
| Autor: | Nabela I. El-Sharkawy, Alklech M. Alklech, Yasmina M. Abd-Elhakim |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Veterinary medicine
cadmium submersion chemistry.chemical_element Adipose tissue Environmental pollution Cadmium chloride Adipocere Biochemistry Genetics and Molecular Biology (miscellaneous) Pathology and Forensic Medicine Analytical Chemistry Iodine value chemistry.chemical_compound Tap water forensic toxicology Physical and Theoretical Chemistry Cadmium K5000-5582 Forensic toxicology Original Articles Criminal law and procedure rats Psychiatry and Mental health chemistry Anthropology Forensic sciences Public aspects of medicine RA1-1270 Research Article adipocere |
| Zdroj: | Forensic Sciences Research article-version (VoR) Version of Record Forensic Sciences Research, Vol 6, Iss 2, Pp 159-167 (2021) |
| ISSN: | 2471-1411 2096-1790 |
| DOI: | 10.1080/20961790.2018.1541537 |
| Popis: | There is a dearth of information on the mutual interaction between metal intoxication and adipocere formation. Herein, 40 adult female albino rats were distributed into two equal groups, one used as control while the other orally administered single dose of cadmium chloride (CdCl2) 225 mg/kg·bw (LDmin). Control group was killed by cervical dislocation. Half of dead rats of both groups were subjected for determination of iodine value and estimation of cadmium (Cd) residues while the other half of both groups were submerged in opened glass container previously filled with 4 L dechlorinated tap water kept in closed room with an open air access (one cadaver/container). Gross morphological changes of submerged cadavers were recorded weekly along the experiment. At the end of the experiment, after 3 months, samples were collected again for iodine value determination and estimation of Cd residues. The obtained results revealed the depressant effect of Cd toxicity on development of adipocere. Cd residues were found in different tissues of cadavers at time of death with the highest amount in the intestines followed by the liver and kidneys, then lungs, adipose tissue, muscles, and finally the bones. After 3 months of water submersion, tissues exhibited significant decrease in the amount of Cd residues but to a limit that was still detected. This study concluded the possibility of detection of Cd residues even after adipocere formation. Additionally, it shed light on the possibility of the interference of environmental pollution with the natural rate of decomposition especially adipocere formation. |
| Databáze: | OpenAIRE |
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