Low pancreatic lipase in insulin-dependent diabetics
| Autor: | R. De Albarran, D. Junglee, Paresh Dandona, D B Freedman, A.G. Beckett, A Katrak |
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| Rok vydání: | 1983 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Pathology and Forensic Medicine Immunoreactive trypsin Internal medicine Diabetes mellitus Diabetes Mellitus medicine Humans Insulin Pancreatic lipase Trypsin Lipase Pancreas biology Chemistry General Medicine medicine.disease medicine.anatomical_structure Endocrinology biology.protein Insulin dependent Research Article medicine.drug |
| Zdroj: | Journal of Clinical Pathology. 36:200-202 |
| ISSN: | 0021-9746 |
| DOI: | 10.1136/jcp.36.2.200 |
| Popis: | Serum samples obtained from 20 insulin-dependent diabetics (IDD), 23 non-insulin-dependent diabetics (NIDD) and 30 controls were assayed for their pancreatic lipase activity, immunoreactive trypsin concentration and glycosylated haemoglobin (HbA1) respectively. The distribution of serum pancreatic lipase activity in normal subjects and diabetics was nonparametric. The median serum lipase activity in IDDs (86 U/l) was significantly lower that that in controls (131 U/l, p less than 0.002) and NIDDs (126 U/l, p less than 0.001). There was a significant correlation between serum pancreatic lipase activity and serum IRT concentration (r = 0.65, p less than 0.001). Neither pancreatic lipase activity nor IRT was related to HbA1 concentrations. These data show for the first time that serum pancreatic lipase activity is diminished in IDDs. |
| Databáze: | OpenAIRE |
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