Institutional Experience with Ostomies Created During Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion
| Autor: | Yongli Shuai, David L. Bartlett, Matthew P. Holtzman, Steven S. Ahrendt, Herbert J. Zeh, James F. Pingpank, Haroon A. Choudry, Heather L. Jones, Lekshmi Ramalingam, Amer H. Zureikat, Sam Pakraftar |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Ostomy medicine.medical_treatment Peritoneal Stomata Anastomosis 03 medical and health sciences Ileostomy 0302 clinical medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Prospective Studies Prospective cohort study Survival rate Peritoneal Neoplasms Retrospective Studies Colectomy Proportional hazards model business.industry Retrospective cohort study Cytoreduction Surgical Procedures Hyperthermia Induced Perioperative Middle Aged Prognosis Combined Modality Therapy Surgery Survival Rate Oncology Chemotherapy Adjuvant Chemotherapy Cancer Regional Perfusion 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology business Follow-Up Studies |
| Zdroj: | Annals of Surgical Oncology. 24:3811-3817 |
| ISSN: | 1534-4681 1068-9265 |
| Popis: | Cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion (CRS-HIPEC) is a complex procedure that often requires ostomy creation to protect high-risk anastomoses. This study aimed to evaluate the authors’ institutional experience with CRS-HIPEC-associated ostomies, determine predictors of ostomy creation and reversal, and assess their impact on survival. The study analyzed clinicopathologic, perioperative, and oncologic data from a prospective database of 1435 CRS-HIPEC procedures for peritoneal metastases. The Kaplan–Meier method was used to estimate survival. Multivariate analyses identified associations with ostomy creation/reversal and survival. Ostomies were created in 34% of the patients, most commonly loop ileostomies (82%). Loop ileostomies were reversed in the majority of patients (83%), whereas non-loop ileostomies were infrequently reversed ( |
| Databáze: | OpenAIRE |
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