Risk over time and risk factors of intraoperative respiratory events: a historical cohort study of 14,153 children
| Autor: | Ngamjit Pattaravit, Maliwan Oofuvong, Kanjana Nuanjun, Alan Geater, Virasakdi Chongsuvivatwong |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Risk over time Cohort Studies Desflurane Laryngeal mask airway Risk Factors Anesthesiology Internal medicine Intraoperative period Respiratory events Medicine Humans Pediatric anesthesia Laryngospasm Child Intraoperative Complications business.industry Proportional hazards model Incidence (epidemiology) Hazard ratio Tertiary care hospital Airway obstruction medicine.disease Respiration Disorders Anesthesiology and Pain Medicine Female medicine.symptom business medicine.drug Research Article |
| Zdroj: | BMC Anesthesiology |
| ISSN: | 1471-2253 |
| Popis: | Background The variation in the rate of intraoperative respiratory events (IRE) over time under anesthesia and the influence of anesthesia-related factors have not yet been described. The objectives of this study were to describe the risk over time and the risk factors for IRE in children at a tertiary care hospital in southern Thailand. Methods The surveillance anesthetic database and chart review of IRE of 14,153 children who received surgery at Songklanagarind Hospital during January 2005 to December 2011 were used to obtain demographic, surgical and anesthesia-related data. Incidence density of IRE per person-time was determined by a Poisson modelling. Risk of IRE over time was displayed using Kaplan Meier survival and Nelson-Aalen curves. Multivariate Cox regression was employed to identify independent predictors for IRE. Adjusted hazard ratios (HR) and their 95% confidence intervals (CI) were obtained from the final Cox model. Results Overall, IRE occurred in 315 out of 14,153 children. The number (%) of desaturation, wheezing or bronchospasm, laryngospasm, reintubation and upper airway obstruction were 235 (54%), 101 (23%), 75 (17%), 21 (5%) and 4 (1%) out of 315 IRE, respectively. The incidence density per 100,000 person-minutes of IRE at the induction period (61.3) was higher than that in the maintenance (13.7) and emergence periods (16.5) (p |
| Databáze: | OpenAIRE |
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