Illicit Drug Use and Risk for USA300 Methicillin-ResistantStaphylococcus aureusInfections with Bacteremia

Autor: O. Colin Stine, J. Kristie Johnson, Mary Claire Roghmann, Kristen Kreisel, Alan J. Lesse, Michael W. Climo, Eli N. Perencevich, Michelle Shardell, Fred M. Gordin
Rok vydání: 2010
Předmět:
Male
Epidemiology
lcsh:Medicine
Bacteremia
Drug resistance
medicine.disease_cause
community-acquired infections
Cohort Studies
Risk Factors
CME
bacteria
Cross Infection
Molecular Epidemiology
Middle Aged
Staphylococcal Infections
Infectious Diseases
Staphylococcus aureus
Female
Methicillin-Resistant Staphylococcus aureus
Microbiology (medical)
medicine.medical_specialty
Substance-Related Disorders
Staphylococcal infections
Article
lcsh:Infectious and parasitic diseases
Internal medicine
mental disorders
medicine
Humans
lcsh:RC109-216
antimicrobial resistance
Epidemics
Intensive care medicine
Veterans Affairs
Aged
Retrospective Studies
business.industry
Research
lcsh:R
biochemical phenomena
metabolism
and nutrition
bacterial infections and mycoses
medicine.disease
Methicillin-resistant Staphylococcus aureus
United States
electrophoresis
Relative risk
bacterial typing techniques
business
illicit drug use
Zdroj: Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 16, Iss 9, Pp 1419-1427 (2010)
ISSN: 1080-6059
1080-6040
DOI: 10.3201/eid1609.091802
Popis: To assess the association of illicit drug use and USA300 methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, a multicenter study was conducted at 4 Veterans Affairs medical centers during 2004–2008. The study showed that users of illicit drugs were more likely to have USA300 MRSA bacteremia (in contrast to bacteremia caused by other S. aureus strains) than were patients who did not use illicit drugs (adjusted relative risk 3.0; 95% confidence interval 1.9–4.4). The association of illicit drug use with USA300 MRSA bacteremia decreased over time (p = 0.23 for trend). Notably, the proportion of patients with USA300 MRSA bacteremia who did not use illicit drugs increased over time. This finding suggests that this strain has spread from users of illicit drugs to other populations.
Databáze: OpenAIRE
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