Vitamin B-12 Concentrations in Breast Milk Are Low and Are Not Associated with Reported Household Hunger, Recent Animal-Source Food, or Vitamin B-12 Intake in Women in Rural Kenya

Autor: Clair Null, John M. Colford, Audrie Lin, Setti Shahab-Ferdows, Sera L. Young, Christine P. Stewart, Anne M Williams, Geoffrey M Nyambane, Lindsay H. Allen, Holly N. Dentz, Daniela Hampel, Caroline J. Chantry, Benjamin F. Arnold, Marion Kiprotich, Beryl Achando
Rok vydání: 2016
Předmět:
Male
0301 basic medicine
Hunger
Medicine (miscellaneous)
chemistry.chemical_compound
Animal source foods
Family Characteristics
animal-source foods
Nutrition and Dietetics
Postpartum Period
Vitamin B 12
Breast Feeding
Dietary Reference Intake
breast milk
Female
Adult
Vitamin
medicine.medical_specialty
Mothers
lactation
Breast milk
hunger
Young Adult
03 medical and health sciences
Animal science
Internal medicine
medicine
Animals
Humans
Lactation
Vitamin B12
Megaloblastic anemia
vitamin B-12
030109 nutrition & dietetics
Milk
Human
business.industry
Infant
Newborn
Infant
Vitamin B 12 Deficiency
Feeding Behavior
Maternal Nutritional Physiological Phenomena
food security
medicine.disease
Kenya
Diet
Community and International Nutrition
Cross-Sectional Studies
Endocrinology
chemistry
Africa
business
Breast feeding
Postpartum period
Zdroj: Williams, AM; Chantry, CJ; Young, SL; Achando, BS; Allen, LH; Arnold, BF; et al.(2016). Vitamin B-12 concentrations in breast milk are low and are not associated with reported household hunger, recent animal-source food, or Vitamin B-12 intake in women in rural Kenya. Journal of Nutrition, 146(5), 1125-1131. doi: 10.3945/jn.115.228189. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/0j08r409
ISSN: 0022-3166
DOI: 10.3945/jn.115.228189
Popis: Author(s): Williams, AM; Chantry, CJ; Young, SL; Achando, BS; Allen, LH; Arnold, BF; Colford, JM; Dentz, HN; Hampel, D; Kiprotich, MC; Lin, A; Null, CA; Nyambane, GM; Shahab-Ferdows, S; Stewart, CP | Abstract: © 2016 American Society for Nutrition. Background: Breast milk vitamin B-12 concentration may be inadequate in regions in which animal-source food consumption is low or infrequent. Vitamin B-12 deficiency causes megaloblastic anemia and impairs growth and development in children. Objective: We measured vitamin B-12 in breast milk and examined its associations with household hunger, recent animalsource food consumption, and vitamin B-12 intake. Methods: In a cross-sectional substudy nested within a cluster-randomized trial assessing water, sanitation, hygiene, and nutrition interventions in Kenya, we sampled 286 women 1-6 mo postpartum. Mothers hand-expressed breast milk 1 min into a feeding after 90 min observed nonbreastfeeding. The Household Hunger Scale was used to measure hunger, food intake in the previous week was measured with the use of a food-frequency questionnaire (FFQ), and vitamin B-12 intake was estimated by using 24-h dietary recall. An animal-source food score was based on 10 items from the FFQ (range: 0-70). Breast milk vitamin B-12 concentration was measured with the use of a solid-phase competitive chemiluminescent enzyme immunoassay and was modeled with linear regression. Generalized estimating equations were used to account for correlated observations at the cluster level. Results: Median (IQR) vitamin B-12 intake was 1.5 μg/d (0.3, 9.7 mg/d), and 60% of women consumed l 2.4 μg/d, the estimated average requirement during lactation. Median (IQR) breast milk vitamin B-12 concentration was 113 pmol/L (61, 199 pmol/L); 89% had concentrations l 310 pmol/L, the estimated adequate concentration. Moderate or severe hunger prevalence was 27%; the animal-source food score ranged from 0 to 30 item-d/wk. Hunger and recent animal-source food and vitamin B-12 intake were not associated with breast milk vitamin B-12 concentrations. Maternal age was negatively associated with breast milk vitamin B-12 concentrations. Conclusion: Most lactating Kenyan women consumed less than the estimated average requirement of vitamin B-12 and had low breast milk vitamin B-12 concentrations. We recommend interventions that improve vitamin B-12 intake in lactating Kenyan women to foster maternal health and child development.
Databáze: OpenAIRE
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