Randomized, controlled trial split-faced study of 595-nm pulsed dye laser in the treatment of acne vulgaris and acne erythema in adolescents and early adulthood
| Autor: | Ramrada Lekwuttikarn, Susheera Chatproedprai, Siriwan Wananukul, Therdpong Tempark |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Erythema Lasers Dye Dermatology Severity of Illness Index law.invention Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Patient satisfaction Randomized controlled trial law Acne Vulgaris Severity of illness medicine Humans Low-Level Light Therapy Young adult Adverse effect Acne business.industry Papule medicine.disease Patient Satisfaction 030220 oncology & carcinogenesis Female medicine.symptom business Facial Dermatoses |
| Zdroj: | International Journal of Dermatology. 56:884-888 |
| ISSN: | 0011-9059 |
| DOI: | 10.1111/ijd.13631 |
| Popis: | The high prevalence of acne vulgaris in teenagers has increased comorbidities. Lasers offer alternative options for acne treatment because they have rapid action, low systemic adverse effects, and do not require everyday treatment. To study the efficacy and patients' satisfaction of 595-nm pulse dye laser (PDL) treatment of acne vulgaris and acne erythema in adolescents and early adulthood, we designed a blocked-randomized, split-faced 595-nm PDL (fluence 8 J/cm3 pulse duration 10 ms, spot size 7 mm, 2 session every 2 weeks) study in patients with mild to moderate acne by comparing the laser-treated and non-treated side. The acne lesion counts, acne erythema grading, and acne severity grading were evaluated at baseline and 2, 4, and 8 weeks. Thirty patients were recruited. The results showed no statistically significant difference except the papule count at week 4 which was -1.828 on the treated side and 0.103 on the non-treated side of the face, P-value 0.0018. There was no statistically significant difference of acne severity grading and acne erythema grading between both sides of the face. The mean scores of patients' satisfaction on the laser-treated side were 75, 81, and 81%, respectively. The PDL treatment in this study reveals no significant improvement in acne therapy; however, the patients were satisfied with this laser treatment. |
| Databáze: | OpenAIRE |
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