Bipolar Syndromes Following Brain Trauma

Autor: M. T. Wright, J. L. Cummings, M. F. Mendez, D. J. Foti
Rok vydání: 1997
Předmět:
Zdroj: Neurocase. 3:111-118
ISSN: 1465-3656
DOI: 10.1093/neucas/3.2.111
Popis: A number of illnesses can produce mood abnormalities. Case reports suggest that syndromes resembling Idiopathic bipolar disorders can follow traumatic brain injuries (TBI). We describe a TBI patient who developed episodes of depression and mania after his injuries and review the recent literature on post-traumatic bipolar syndromes. While unipolar depression is common after TBI, bipolar syndromes occur in only a small segment of the TBI population. A bipolar syndrome can appear immediately after a TBI or after a delay of months or years. Patients with post-traumatic mania are often irritable and aggressive. Factors that may predispose a TBI patient to bipolar illness include an inherited vulnerability to mood disorders, pre-existent frontal subcortical and diencephalic atrophy, and post-traumatic seizures. Studies of patients who developed a bipolar syndrome after a brain Insult show a preponderance of right hemisphere lesions, particularly right orbitofrontal and basotemporal cortical, caudate a...
Databáze: OpenAIRE