Reliability of the PROFUND index to predict 4-year mortality in polypathological patients
| Autor: | Begoña de Escalante Yangüela, Jesús Díez-Manglano, María del Mar Rodero Roldán, Esther del Corral Beamonte, María Pilar Lambán Aranda, Rosa Ramos Ibáñez, Concepción Ortiz Domingo, Eulalia Munilla López, Carla Toyas Miazza |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Index (economics) 030204 cardiovascular system & hematology Risk Assessment Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Internal medicine Internal Medicine medicine Humans Cognitive deterioration Prospective Studies 030212 general & internal medicine Mortality Prospective cohort study Aged Aged 80 and over Geriatrics business.industry Area under the curve Multimorbidity Reproducibility of Results Mean age Middle Aged Prognosis Hospitalization ROC Curve Spain Delirium Female medicine.symptom business Follow-Up Studies |
| Zdroj: | Medicina Clínica (English Edition). 147:238-244 |
| ISSN: | 2387-0206 |
| DOI: | 10.1016/j.medcle.2016.10.016 |
| Popis: | Objective To determine the usefulness of the PROFUND index to assess the risk of global death after 4 years in polypathological patients. Patients and methods Multicentre prospective cohort (Internal Medicine and Geriatrics) study. Polypathological patients admitted between March 1st and June 30th 2011 were included. For each patient, data concerning age, sex, living at home or in a nursing residence, polypathology categories, Charlson, Barthel and Lawton–Brody indexes, Pfeiffer questionnaire, socio-familial Gijon scale, delirium , number of drugs, haemoglobin and creatinine values were gathered, and the PROFUND index was calculated. The follow-up lasted 4 years. Results We included 441 patients, 324 from Internal Medicine and 117 from Geriatrics, with a mean age of 80.9 (8.7) years. Of them, 245 (55.6%) were women. Heart (62.7%), neurological (41.4%) and respiratory (37.3%) diseases were the most frequent. Geriatrics inpatients were older and more dependants and presented greater cognitive deterioration. After 4 years, 335 (76%) patients died. Mortality was associated with age, dyspnoea, Barthel index delirium , advanced neoplasia and ≥4 admissions in the last year. The area under the curve of the PROFUND index was 0.748, 95% CI 0.689–0.806, p p = 0.818 in Geriatrics patients, respectively. Conclusions The PROFUND index is a reliable tool for predicting long-term global mortality in polypathological patients from Internal Medicine but not from Geriatrics departments. |
| Databáze: | OpenAIRE |
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