Continuous Intraoperative Intraperitoneal Hyperthermic Chemoperfusion (CIIPHCP) in the Treatment of Advanced Stage and Recurrent Granulosa Cell Tumors. Report of Two Cases
| Autor: | Konstantinos J Manolas, G Minopoulos, S. Economou, N. Chatzigeorgiou, K. Chatzigeorgiou, G. Zafiriou |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Adult
Hyperthermia Oncology endocrine system medicine.medical_specialty Time Factors Ovarian Granulosa Cell medicine.medical_treatment Antineoplastic Agents Fatal Outcome Recurrence Internal medicine Humans Medicine Granulosa Cell Tumor Neoplasm Staging Ovarian Neoplasms Cisplatin Intraoperative Care business.industry Advanced stage Obstetrics and Gynecology Hyperthermia Induced Middle Aged medicine.disease Debulking Granulosa cell tumors Perfusion Radiation therapy Female business Adjuvant medicine.drug |
| Zdroj: | Zentralblatt für Gynäkologie. 124:374-377 |
| ISSN: | 1438-9762 0044-4197 |
| DOI: | 10.1055/s-2002-35536 |
| Popis: | Background: Treatment of advanced stages and recurrent ovarian granulosa cell tumors, has not been established yet. The effectiveness of radiation therapy could not be proven. Systemic chemotherapy has shown promising results, but with severe side effects and high incidence of relapse. Case Reports: We report of one patient with advanced stage III C, and one patient with bulky recurrent ovarian granulosa cell tumors. Both patients were treated with a combination of surgical debulking, Continuous Intraoperative Intraperitoneal Hyperthermic Chemoperfusion (CIIPHCP) with Cisplatin and one of them with adjuvant systemic chemotherapy. Conclusion: CIIPHCP appears to offer a promising procedure in addition to surgical debulking and systemic chemotherapy for treatment of advanced or recurrent ovarian granulosa cell tumors. The present report is the first concerning the question of adding Intraoperative Hyperthermic Chemoperfusion in the treatment of advanced or recurrent ovarian granulosa cell tumors. |
| Databáze: | OpenAIRE |
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