Exercise and heat stress : Inflammation and the iron regulatory response
| Autor: | Peter Peeling, Rachel McCormick, Alannah K A McKay, Nicolin Tee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Hot Temperature Iron Medicine (miscellaneous) Inflammation 030204 cardiovascular system & hematology Heat Stress Disorders 03 medical and health sciences 0302 clinical medicine Treadmill running Environmental temperature Animal science Hepcidin Heart rate medicine Humans Orthopedics and Sports Medicine iron metabolism hot environments Serum ferritin Exercise Nutrition and Dietetics biology Chemistry temperature 030229 sport sciences General Medicine Venous blood Heat stress biology.protein athlete hepcidin medicine.symptom heat training Heat-Shock Response |
| Popis: | This study determined the impact of heat stress on postexercise inflammation and hepcidin levels. Twelve moderately trained males completed three, 60-min treadmill running sessions under different conditions: (a) COOL, 18 °C with speed maintained at 80% maximum heart rate; (b) HOTHR, 35 °C with speed maintained at 80% maximum heart rate; and (c) HOTPACE, 35 °C completed at the average running speed from the COOL trial. Venous blood samples were collected pre-, post-, and 3-hr postexercise and analyzed for serum ferritin, interleukin-6 (IL-6), and hepcidin concentrations. Average HR was highest during HOTPACE compared with HOTHR and COOL (p HR compared with COOL and HOTPACE (p PACE (295%; p = .003). No differences in the IL-6 response immediately postexercise between COOL (115%) and HOTHR (116%) were evident (p = .992). No differences in hepcidin concentrations between the three trials were evident at 3 hr postexercise (p = .407). Findings from this study suggest the IL-6 response to exercise is greatest in hot compared with cool conditions when the absolute running speed was matched. No differences in IL-6 between hot and cool conditions were evident when HR was matched, suggesting the increased physiological strain induced from training at higher intensities in hot environments, rather than the heat per se, is likely responsible for this elevated response. Environmental temperature had no impact on hepcidin levels, indicating that exercising in hot conditions is unlikely to further impact transient alterations in iron regulation, beyond that expected in temperate conditions. |
| Databáze: | OpenAIRE |
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