Lymphangioleiomyomatosis A Series of Three Case Reports Illustrating the Link with High Oestrogen States
| Autor: | P.H. Brown, A.M. Wilson, A. Grove, F.A. Carey, H.L. Slack, T. Taylor, S.A. Soosay, J H Winter |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Spirometry medicine.medical_specialty 030204 cardiovascular system & hematology Lung Disorder 03 medical and health sciences 0302 clinical medicine Pregnancy medicine Humans Lymphangioleiomyomatosis 030212 general & internal medicine Lung medicine.diagnostic_test business.industry Hyperprolactinaemia Pneumothorax General Medicine Middle Aged respiratory system medicine.disease Respiratory Function Tests respiratory tract diseases Pregnancy Complications Menopause medicine.anatomical_structure Female Radiology Chest radiograph business |
| Zdroj: | Scottish Medical Journal. 46:150-152 |
| ISSN: | 2045-6441 0036-9330 |
| DOI: | 10.1177/003693300104600509 |
| Popis: | Lymphangioleiornyomatosis is a rare lung disorder characterised by cystic air spaces and smooth muscle proliferation. The condition, which most commonly presents with dyspnoea, pneumothoraces or cough, is only described in fernales and is most commonly diagnosed during childbearing years. Three cases are presented which illustrate typical features of the disease and the association with high oestrogen levels. The first had recurrent pneumothoraces during her first pregnancy. The second lady was post menopausal at diagnosis but her symptoms predated her menopause. The third, presented with dyspnoea, abnormal chest sensations and a pneumothorax. She had a history of hyperprolactinaemia with secondary amenorhoea due to low oestrogen levels which had been corrected prior to her presentation. All three patients had reduced gas transfer and abnormalities in spirometry, two had reticular shadowing on their chest radiograph and all had typical appearances on lung computerised tomography. Although disease progression was variable, all patients showed a gradual decline in lung function. |
| Databáze: | OpenAIRE |
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