High prevalence of the hepatitis C virus infection among the inpatients of schizophrenia and psychoactive substance abuse in Japan
| Autor: | Osamu Ida, Naoki Minami, Masayuki Morikawa, Kunya Yamamoto, Eiji Miyoshi, Motoasa Koh, Norio Hayashi, Akihiro Tokuyama, Yu Nakamura, Yoshiharu Honda, Tatsuji Nagano, Motoharu Hirai, Akinori Kasahara, Toshifumi Kishimoto, Junzo Iida |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Hospitalized patients Substance-Related Disorders Hepatitis C virus Amphetamine-Related Disorders Psychoactive substance Blood Donors medicine.disease_cause Japan Internal medicine medicine Humans Psychiatry Biological Psychiatry Pharmacology Hepatitis Inpatients Sex Characteristics High prevalence biology business.industry Age Factors Hepatitis C Antibodies medicine.disease Hepatitis C Alcoholism Schizophrenia biology.protein Female Antibody business Psychoactive substance abuse |
| Zdroj: | Progress in neuro-psychopharmacologybiological psychiatry. 28(3) |
| ISSN: | 0278-5846 |
| Popis: | Prevalence of anti-HCV antibody in 1193 hospitalized patients (848 males and 345 females) in psychiatric department was investigated. Overall prevalence ratio was 9.1%, indicating significantly higher than that of healthy blood donors. In the classification of ICD-10, the prevalence of the inpatients diagnosed in schizophrenia group and psychoactive substance use group accounted for 6.2% and 13.8%, respectively. However, adequate reasons such as sanitary issues were not found to account for the high prevalence. Only the age of the patients could account for the high prevalence in the schizophrenic group. In the psychoactive substance abuse group, the sanitary issues might be a major cause of the very high prevalence of anti-HCV antibody, while other factors such as dysfunction of the immune system might be considered to account for it. |
| Databáze: | OpenAIRE |
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