Sequence, expression, and location of Zebrafish frizzled 10
| Autor: | Spencer Hermanson, Stephen C. Ekker, Aidas Nasevicius, Tana M. Hyatt |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Tail
Frizzled Embryology Embryo Nonmammalian Molecular Sequence Data Receptors Cell Surface Receptors G-Protein-Coupled medicine Animals Gene family Radiation hybrid mapping Amino Acid Sequence Zebrafish Gene Genetics biology Wnt signaling pathway Neural tube Brain Chromosome Mapping Gene Expression Regulation Developmental Gastrula Zebrafish Proteins biology.organism_classification Frizzled Receptors Transmembrane protein medicine.anatomical_structure Head Developmental Biology |
| Zdroj: | Mechanisms of Development. 92(2):311-314 |
| ISSN: | 0925-4773 |
| DOI: | 10.1016/s0925-4773(00)00244-6 |
| Popis: | Members of the frizzled gene family encode seven-pass transmembrane proteins that function in the interpretation and reception of Wnt-mediated cell-cell communication events. To investigate frizzled function in early zebrafish development, we isolated the maternally contributed frizzled 10 (fz10) gene and localized it to linkage group 8 using radiation hybrid mapping. The cloned zebrafish fz10 is closely related to the fz10 group from other organisms. Zygotic expression of fz10 is observed in the posterior tail mesenchyme, dorsal neural tube, and different parts of the brain. |
| Databáze: | OpenAIRE |
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