Uveitis-like syndrome and iris transillumination after the use of oral moxifloxacin
| Autor: | E Van Aken, J P Martinez Ciriano, P W T De Waard, L van Langenhove, M Wefers Bettink-Remeijer, K Brouwers, T O Missotten |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Photophobia Moxifloxacin Administration Oral Transillumination Pupil Uveitis Anti-Infective Agents Ophthalmology medicine Paralysis Humans Antibacterial agent Aged Aza Compounds business.industry medicine.disease Surgery Sphincter paralysis Iris Diseases Quinolines Female medicine.symptom business medicine.drug Fluoroquinolones |
| Zdroj: | Eye (London, England). 23(12) |
| ISSN: | 1476-5454 |
| Popis: | To report a newly recognized adverse effect of oral moxifloxacin. Observational case reports. Five patients who used oral moxifloxacin therapy. In five patients, a uveitis-like episode followed oral moxifloxacin therapy, afterwards they experienced photophobia. At slitlamp investigation, the patients showed almost complete iris transillumination, not restricted to one sector, and persistent mydriasis of the pupil, with no reaction to light and no near reflex. Follow-up of 3 years in one of the patients showed no change of symptoms. Only in one patient, with a history of anterior uveitis, an anterior chamber tap was positive for herpes simplex genome. Only after the use of moxifloxacin did she experience continuous photophobia. Iris transillumination and sphincter paralysis is a newly recognized adverse effect of oral moxifloxacin therapy. |
| Databáze: | OpenAIRE |
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