An integrative view of mammalian seasonal neuroendocrinology
| Autor: | Cristina Sáenz de Miera, Francis J. P. Ebling, Shona H. Wood, Hugues Dardente |
|---|---|
| Přispěvatelé: | Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Department of Arctic and Marine Biology, Arctic University of Norway, School of Life Sciences, University of Nottingham, UK (UON), University of Michigan [Ann Arbor], University of Michigan System, Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Thyroid Hormones
medicine.medical_specialty Endocrinology Diabetes and Metabolism [SDV]Life Sciences [q-bio] Ependymoglial Cells Hypothalamus Neuropeptide 030209 endocrinology & metabolism melatonin Neuroendocrinology Biology photoperiod Melatonin tanycytes 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Endocrinology Kisspeptin Circadian Clocks Internal medicine medicine VDP::Mathematics and natural science: 400::Zoology and botany: 480 Animals Humans [INFO]Computer Science [cs] Neurons Pituitary stalk Endocrine and Autonomic Systems Neurosecretory Systems thyroid hormone Prolactin seasonal remodelling Pituitary Gland Seasons Pars tuberalis 030217 neurology & neurosurgery medicine.drug VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 pars tuberalis |
| Zdroj: | Journal of Neuroendocrinology 9th International Congress of Neuroendocrinology 9th International Congress of Neuroendocrinology, Jul 2018, Toronto, Canada. pp.17, ⟨10.1111/jne.12729⟩ |
| DOI: | 10.1111/jne.12729⟩ |
| Popis: | This is the peer reviewed version of the following article: Dardente, H., Wood, S.H., Ebling, F. & Sáenz de Miera, C. (2019). An integrative view of mammalian seasonal neuroendocrinology. Journal of neuroendocrinology. Journal of Neuroendocrinology, 31(5), e12729, which has been published in final form at https://doi.org/10.1111/jne.12729. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Seasonal neuroendocrine cycles that govern annual changes in reproductive activity, energy metabolism and hair growth are almost ubiquitous in mammals that have evolved at temperate and polar latitudes. Changes in nocturnal melatonin secretion regulating gene expression in the pars tuberalis (PT) of the pituitary stalk are a critical common feature in seasonal mammals. The PT sends signal(s) to the pars distalis of the pituitary to regulate prolactin secretion and thus the annual moult cycle. The PT also signals in a retrograde manner via thyroid‐stimulating hormone to tanycytes, which line the ventral wall of the third ventricle in the hypothalamus. Tanycytes show seasonal plasticity in gene expression and play a pivotal role in regulating local thyroid hormone (TH) availability. Within the mediobasal hypothalamus, the cellular and molecular targets of TH remain elusive. However, two populations of hypothalamic neurones, which produce the RF‐amide neuropeptides kisspeptin and RFRP3 (RF‐amide related peptide 3), are plausible relays between TH and the gonadotrophin‐releasing hormone‐pituitary‐gonadal axis. By contrast, the ways by which TH also impinges on hypothalamic systems regulating energy intake and expenditure remain unknown. Here, we review the neuroendocrine underpinnings of seasonality and identify several areas that warrant further research. |
| Databáze: | OpenAIRE |
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