Low-dose prednisolone treatment in Duchenne and Becker muscular dystrophy
| Autor: | K.G. Henriksson, E. Bäckman |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Test battery medicine.medical_specialty Adolescent Prednisolone Duchenne muscular dystrophy Placebo Muscular Dystrophies Excessive weight gain Double-Blind Method medicine Humans Muscular dystrophy Child Genetics (clinical) Muscle force business.industry Muscles Low dose medicine.disease Neurology Child Preschool Anesthesia Pediatrics Perinatology and Child Health Physical therapy Neurology (clinical) business medicine.drug |
| Zdroj: | Neuromuscular Disorders. 5:233-241 |
| ISSN: | 0960-8966 |
| DOI: | 10.1016/0960-8966(94)00048-e |
| Popis: | Forty-one boys, aged 4.0–19.4 yr, with Duchenne or Becker muscular dystrophy, took part in a 12-month randomized, double-blind cross-over trial in which the patients received 0.35 mg kg −1 day −1 prednisolone for six months and placebo for six months. One patient stopped the treatment because of excessive weight gain. The boys were assessed every third month with a comprehensive test battery of muscle force and function. The results support earlier reports that prednisolone treatment can either improve muscle force and function or diminish the deterioration of muscle function in both Becker and Duchenne muscular dystrophy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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