Reactivation of dormant cutaneous Leishmania infection in a kidney transplant patient
| Autor: | Marjan Mirzabeigi, Gaetano Ciancio, Sean Baraniak, Uzma Farooq, Vladimir Vincek, Lorraine Dowdy |
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| Rok vydání: | 2006 |
| Předmět: |
Graft Rejection
Pathology medicine.medical_specialty Histology Mucocutaneous zone Antiprotozoal Agents Leishmaniasis Cutaneous Dermatology Opportunistic Infections Pathology and Forensic Medicine Immunocompromised Host Cutaneous leishmaniasis Amphotericin B medicine Humans Phlebotomus Skin Diseases Infectious biology business.industry Leishmaniasis Middle Aged biology.organism_classification medicine.disease Leishmania Kidney Transplantation Sandfly Transplantation Visceral leishmaniasis Immunology Female business Immunosuppressive Agents |
| Zdroj: | Journal of Cutaneous Pathology. 33:701-704 |
| ISSN: | 1600-0560 0303-6987 |
| DOI: | 10.1111/j.1600-0560.2006.00532.x |
| Popis: | Background: Leishmaniasis is an infection caused by a protozoan parasite belonging to genus Leishmania and transmitted by the Phlebotomus sandfly. Clinical presentations of infection include visceral, cutaneous, and mucocutaneous forms. Leishmaniasis is endemic in Africa, Asia, Europe, South America, and southern part of North America. This infection is extremely rare in the US and is mostly found among travelers coming from endemic areas. Cases of cutaneous and visceral leishmaniasis have been reported in organ transplant recipients in endemic areas. Case report: We describe a case of cutaneous leishmaniasis in a kidney transplant patient, originally from Bolivia, who resides in the area known to be non-endemic for leishmaniasis and who is known not to travel within or outside of the US after the transplantation. Results: Histologic examination of cutaneous lesion revealed extensive subcutaneous lymphohistiocytic inflammation with clusters of amastigote within histiocytes. Conclusion: To our knowledge, this is the first case of cutaneous leishmaniasis in a kidney transplant patient residing in the US in an area known to be non-endemic for leishmaniasis, probably after reactivation of a previously dormant infection acquired outside of the US at least 9 months prior to developing clinical symptoms. |
| Databáze: | OpenAIRE |
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