Additional complex fractionated atrial electrogram ablation does not improve the outcomes of non-paroxysmal atrial fibrillation: A systematic review and meta-analysis of randomized controlled trials
Autor: | Indra Jabbar Aziz, Dion Setiawan, Yoga Waranugraha, Ardian Rizal |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
RD1-811 medicine.medical_treatment Catheter ablation 030204 cardiovascular system & hematology Pulmonary vein isolation Non-paroxysmal atrial fibrillation Pulmonary vein law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Heart Conduction System Internal medicine Atrial Fibrillation medicine Diseases of the circulatory (Cardiovascular) system Humans 030212 general & internal medicine Heart Atria Randomized Controlled Trials as Topic business.industry Atrial fibrillation medicine.disease Ablation Confidence interval CFAE ablation RC666-701 Meta-analysis Relative risk Cardiology Catheter Ablation Surgery Original Article Cardiology and Cardiovascular Medicine business Electrophysiologic Techniques Cardiac |
Zdroj: | Indian Heart Journal Indian Heart Journal, Vol 73, Iss 1, Pp 63-73 (2021) |
ISSN: | 2213-3763 0019-4832 |
Popis: | Background: Non-paroxysmal atrial fibrillation (AF) has a complex pathophysiological process. The standard catheter ablation approach is pulmonary vein isolation (PVI). The additional value of complex fractionated electrogram (CFAE) ablation is still unclear. We aimed to investigate the additional value of CFAE ablation for non-paroxysmal AF. Methods: We performed a systematic review and meta-analysis of randomized controlled studies up to May 2020. Articles comparing pulmonary vein isolation (PVI) plus CFAE ablation and PVI alone for AF were obtained from the electronic scientific databases. The pooled mean difference (MD) and pooled risk ratio (RR) were assessed. Results: A total of 8 randomized controlled trials (RCTs) including 1034 patients were involved. Following a single catheter ablation procedure, the presence of any atrial tachyarrhythmia (ATA) with or without the use of antiarrhythmic drugs (AADs) between both groups were not significantly different (RR = 1.1; 95% confidence interval [CI] = 0.97–1.24; p = 0.13). Similar results were also obtained for the presence of any ATA without the use of AADs (RR = 1.08; 95% CI = 0.96–1.22; p = 0.2). The additional CFAE ablation took longer procedure times (MD = 46.95 min; 95% CI = 38.27–55.63; p = |
Databáze: | OpenAIRE |
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