Original Protocol Using Computed Tomographic Angiography for Diagnosis of Brain Death: A Better Alternative to Standard Two-Phase Technique?
| Autor: | Anna Walecka, Marcin Sawicki, Jerzy Walecki, Piotr Skrzywanek, Wojciech Poncyljusz, Krzysztof Safranow, Romuald Bohatyrewicz, Małgorzata Burzyńska, Witold Mańko, Olgierd Rowiński, Joanna Sołek-Pastuszka, Z. Czajkowski, Maciej Guziński, Krzysztof Jurczyk |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Brain Death medicine.medical_specialty Adolescent medicine.medical_treatment Cerebral arteries Sensitivity and Specificity Young Adult Text mining Multicenter trial medicine Humans Prospective Studies cardiovascular diseases Prospective cohort study Aged Transplantation medicine.diagnostic_test business.industry musculoskeletal neural and ocular physiology General Medicine Middle Aged Cerebral Angiography Computed tomographic angiography Angiography Female Decompressive craniectomy Radiology Tomography X-Ray Computed business psychological phenomena and processes Cerebral angiography |
| Zdroj: | ResearcherID |
| ISSN: | 2329-0358 |
| DOI: | 10.12659/aot.893808 |
| Popis: | BACKGROUND The application of computed tomographic angiography (CTA) for the diagnosis of brain death (BD) is limited because of the low sensitivity of the commonly used two-phase method consisting of assessing arterial and venous opacification at the 60th second after contrast injection. The hypothesis was that a reduction in the scanning delay might increase the sensitivity of the test. Therefore, an original technique using CTA was introduced and compared with catheter angiography as a reference. MATERIAL AND METHODS In a prospective multicenter trial, 84 clinically brain-dead patients were examined using CTA and catheter angiography. The sensitivities of original CTA technique, involving an arterial assessment at the 25th second and a venous assessment at the 40th second, and the standard CTA, involving an arterial and venous assessment at the 60th second, were compared to catheter angiography. RESULTS Catheter angiography results were consistent with the clinical diagnosis of BD in all cases. In comparison to catheter angiography, the sensitivity of original CTA technique was 0.93 (95%CI, 0.85-0.97; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|