Asymptomatic School-Aged Children Are Important Drivers of Malaria Transmission in a High Endemicity Setting in Uganda
| Autor: | John Rek, Sara Lynn Blanken, Joseph Okoth, Daniel Ayo, Ismail Onyige, Eric Musasizi, Jordache Ramjith, Chiara Andolina, Kjerstin Lanke, Emmanuel Arinaitwe, Peter Olwoch, Katharine A Collins, Moses R Kamya, Grant Dorsey, Chris Drakeley, Sarah G Staedke, Teun Bousema, Melissa D Conrad |
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| Rok vydání: | 2022 |
| Předmět: |
Adolescent
Plasmodium falciparum lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] Burkitt Lymphoma Malaria Women's cancers Radboud Institute for Health Sciences [Radboudumc 17] lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] Infectious Diseases Child Preschool Anopheles Animals Humans Immunology and Allergy Uganda Malaria Falciparum Child Asymptomatic Infections |
| Zdroj: | The Journal of Infectious Diseases The Journal of Infectious Diseases, 226, 4, pp. 708-713 The Journal of Infectious Diseases, 226, 708-713 |
| ISSN: | 1537-6613 0022-1899 |
| Popis: | Contains fulltext : 282499.pdf (Publisher’s version ) (Open Access) Achieving malaria elimination requires a better understanding of the transmissibility of human infections in different transmission settings. This study aimed to characterize the human infectious reservoir in a high endemicity setting in eastern Uganda, using gametocyte quantification and mosquito feeding assays. In asymptomatic infections, gametocyte densities were positively associated with the proportion of infected mosquitoes (β = 1.60; 95% CI, 1.32-1.92; P |
| Databáze: | OpenAIRE |
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