Testicular plasmacytoma misdiagnosed as orchitis
| Autor: | Attaya Suvannasankha, Christopher Schiavo, Jesse Mer, Steven A. Mann |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Erythema medicine.medical_treatment Orchitis 03 medical and health sciences 0302 clinical medicine Testicular Neoplasms immune system diseases Positron Emission Tomography Computed Tomography Antineoplastic Combined Chemotherapy Protocols medicine Humans Retroperitoneal Neoplasms Diagnostic Errors In Situ Hybridization Fluorescence Multiple myeloma Aged Ultrasonography Chemotherapy business.industry Ultrasound Neoplasms Second Primary Ultrasonography Doppler General Medicine medicine.disease Chemotherapy regimen Reminder of Important Clinical Lesson Anti-Bacterial Agents medicine.anatomical_structure 030220 oncology & carcinogenesis Plasmacytoma Bone marrow Radiology medicine.symptom Multiple Myeloma business 030215 immunology |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| Popis: | Testicular plasmacytomas are rare, accounting for only 1.3% of all extramedullary plasmacytomas. The infrequency in which it is encountered, coupled with its non-specific clinical and sonographic presentation, makes its diagnosis a challenge. We present a case of a 70-year-old man with multiple myeloma, which was systemically responding to chemotherapy, who developed testicular swelling, erythema and pain. Ultrasound findings were concerning for infection, although urine and serum testing were unremarkable. The patient did not improve after several rounds of antibiotics prompting further evaluation. The patient underwent radical orchiectomy which revealed testicular plasmacytoma. Fluorescent in situ hybridisation (FISH) of the testicular tissue noted mutations which had not been present in the FISH analysis of bone marrow. Positron emission tomography scan later revealed new retroperitoneal plasmacytomas involving the new clone and his chemotherapy regimen needed to be adjusted for treatment. |
| Databáze: | OpenAIRE |
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