Measuring the impact of genetic knowledge on intentions and attitudes of the community towards expanded preconception carrier screening
| Autor: | Hayley Christian, Alethea Rea, Denise Howting, Gianina Ravenscroft, Royston Ong, Caron Molster, Pauline Charman, Nigel G. Laing |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Health Knowledge Attitudes Practice Decision Making Reproductive medicine Intention to use Genetic Counseling Intention 030105 genetics & heredity Logistic regression Developmental psychology Religiosity 03 medical and health sciences Genetics medicine Humans Confidentiality Public Health Surveillance Community Health Services Genetic Testing Genetics (clinical) Demography Apprehension Genetic Carrier Screening Australia Patient Acceptance of Health Care Test (assessment) Cross-Sectional Studies Socioeconomic Factors Female medicine.symptom Preconception Care Carrier screening Psychology |
| Zdroj: | Journal of medical genetics. 55(11) |
| ISSN: | 1468-6244 |
| Popis: | BackgroundPreconception carrier screening (PCS) provides the potential to empower couples to make reproductive choices before having an affected child. An important question is what factors influence the decision to use or not use PCS.MethodsWe analysed the relationship between knowledge, attitudes and intentions to participate in PCS using logistic regression in 832 participants in Western Australia.ResultsTwo-thirds of participants said they would take the test, with 92% of these supporting screening for diseases reducing the lifespan of children and infants. Those who had good genetic knowledge were seven times more likely to intend to use PCS (p≤0.001), while those with high genetic knowledge were four times more likely to (p=0.002) and raised concerns such as insurance and confidentiality.Decreasing genetic knowledge correlated positively with religiosity and apprehension (p≤0.001), which correlated negatively with intention to use PCS (p≤0.001). Increasing genetic knowledge correlated positively with factors representing positive attitudes (p≤0.001), which correlated positively with intention to use PCS (p≤0.001). Many participants with good genetic knowledge nevertheless answered questions that tested understanding incorrectly.80% of participants stated they would prefer to access the test through their general practitioners and 30% would pay up to $A200.ConclusionsKnowledge is instrumental in influencing participation. Having good genetic knowledge may not be enough to understand core concepts of PCS and may impact informed decision-making. This study recommends that continuous education of health professionals and thus the community, in PCS is crucial to reduce misconceptions. |
| Databáze: | OpenAIRE |
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