Synthesis of exemestane labelled with 13C
| Autor: | Enrico Di Salle, Erminia Fontana, Danilo Giribone, Alberto Pignatti |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Pharmacology
Carbon Isotopes Aromatase inhibitor Chemistry medicine.drug_class medicine.medical_treatment Organic Chemistry Clinical Biochemistry Biochemistry Steroid Androstadienes chemistry.chemical_compound Endocrinology Exemestane Isotope Labeling medicine Testosterone Exemestano Molecular Biology Steroidal Aromatase Inhibitor |
| Zdroj: | Steroids. 73:760-764 |
| ISSN: | 0039-128X |
| DOI: | 10.1016/j.steroids.2008.02.010 |
| Popis: | The synthesis of exemestane (Aromasin®), an irreversible steroidal aromatase inhibitor, specifically labelled with 13C is reported. The preparation of [13C3]exemestane was achieved according to an eight-step procedure starting from the commercially available testosterone. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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