Independent mapping methods reveal rotational activation near pulmonary veins where atrial fibrillation terminates before pulmonary vein isolation

Autor:	Paul J. Wang, Tina Baykaner, Rachita Navara, Gabriela Meckler, Sanjiv M. Narayan, Christopher A.B. Kowalewski, F. Shenasa, George Leef, Paul C. Zei, Shirley Park, Junaid A.B. Zaman, Mintu P. Turakhia, Mohan N. Viswanathan, Albert J. Rogers
Rok vydání:	2018
Předmět:	Male medicine.medical_specialty Time Factors medicine.medical_treatment Action Potentials Catheter ablation 030204 cardiovascular system & hematology Article Pulmonary vein Lesion 03 medical and health sciences 0302 clinical medicine Heart Rate Predictive Value of Tests Physiology (medical) Internal medicine Atrial Fibrillation Heart rate medicine Humans Sinus rhythm 030212 general & internal medicine Phase mapping Aged business.industry Body Surface Potential Mapping Atrial fibrillation Middle Aged Ablation medicine.disease Treatment Outcome Pulmonary Veins Catheter Ablation Cardiology Female medicine.symptom Electrophysiologic Techniques Cardiac Cardiology and Cardiovascular Medicine business
Zdroj:	Journal of Cardiovascular Electrophysiology. 29:687-695
ISSN:	1045-3873
Popis:	OBJECTIVE To investigate mechanisms by which atrial fibrillation (AF) may terminate during ablation near the pulmonary veins before the veins are isolated (PVI). INTRODUCTION It remains unstudied how AF may terminate during ablation before PVs are isolated, or how patients with PV reconnection can be arrhythmia-free. We studied patients in whom PV antral ablation terminated AF before PVI, using two independent mapping methods. METHODS We studied patients with AF referred for ablation, in whom biatrial contact basket electrograms were studied by both an activation/phase mapping method and by a second validated mapping method reported not to create false rotational activity. RESULTS In 22 patients (age 60.1 ± 10.4, 36% persistent AF), ablation at sites near the PVs terminated AF (77% to sinus rhythm) prior to PVI. AF propagation revealed rotational (n = 20) and focal (n = 2) patterns at sites of termination by mapping method 1 and method 2. Both methods showed organized sites that were spatially concordant (P
Databáze:	OpenAIRE
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