Breast angiosarcoma one year after adenosquamous endometrial cancer — diagnostic pitfalls
| Autor: | Darko Zdravkovic, Srdjan Dikic, Biljana Sredic, Svetlana Oprić, Dragoljub Bilanovic, Borislav Toskovic, Nebojsa Ivanovic, Tomislav Randjelovic, Dejan Nikolic, Marija Zdravkovic, Miroslav Granic |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment primary breast tumors 03 medical and health sciences 0302 clinical medicine Breast cancer Endometrial Adenosquamous Carcinoma concomitant malignancies medicine Mammography Angiosarcoma Radical Hysterectomy Breast ultrasound Radical mastectomy 030304 developmental biology 0303 health sciences angiosarcoma medicine.diagnostic_test radical mastectomy business.industry Endometrial cancer General surgery General Medicine medicine.disease 3. Good health 030220 oncology & carcinogenesis Medicine Radiology business |
| Zdroj: | Open Medicine, Vol 8, Iss 1, Pp 52-55 (2013) |
| ISSN: | 2391-5463 |
| Popis: | Angiosarcoma of the breast is a rare and very aggressive tumors originated from endothelial cells lining blood vessels. We report a case of a 55-year-old postmenopausal female with a primary breast angiosarcoma diagnosed just a one year after radical hysterectomy and radiation therapy due to endometrial cancer. The patient initially presented with postmenopausal bleeding. Cytology and biopsy of the endometrium were performed and endometrial adenosquamous carcinoma was diagnosed followed by radical hysterectomy and postoperative local radiatiotherapy (50 Gy). One year later patient presented with a great painful tumorous mass in the right breast. Physical examination revealed an oval tumor, located in upper and outer quadrant of the right breast, around 15 cm in diameter. Mammography and ultrasonography were performed. The angiosarcoma of the breast was confirmed by biopsy. The patient underwent radical mastectomy. Histopathology proved the diagnosis of angiosarcoma (high-grade, numerous mitoses over 10/10 HPF, necrosis, “blood lakes”, infiltrative borders). Differential diagnosis of a breast angiosarcoma should be considered in all painful breast tumours no mather the time and the location of the previous radiation treatment even if benign characteristics of these masses have been detected by mammography and breast ultrasound. |
| Databáze: | OpenAIRE |
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