The musculoskeletal manifestations of cystic fibrosis
| Autor: | Perry J. Rush, Henry Levison, Mary Corey, Abraham Shore, Dan M. Wilmot, Craig Coblentz |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Lung Diseases Male medicine.medical_specialty Adolescent Cystic Fibrosis Kyphosis Arthritis Disease Cystic fibrosis Sex Factors Rheumatology HLA Antigens Internal medicine Synovitis medicine Back pain Humans Child business.industry Body Weight Osteoarthropathy Secondary Hypertrophic Age Factors Infant Newborn Infant medicine.disease Body Height Anti-Bacterial Agents Surgery Chronic infection Anesthesiology and Pain Medicine Child Preschool Etiology Female Joint Diseases medicine.symptom business |
| Zdroj: | Seminars in Arthritis and Rheumatism. 15:213-225 |
| ISSN: | 0049-0172 |
| DOI: | 10.1016/0049-0172(86)90018-1 |
| Popis: | Twenty-seven patients with CF and joint complaints were reviewed. Twelve patients had arthritis, 11 had HPO, and four had symptoms of mechanical neck and back pain. We have confirmed the association of CF with an episodic form of arthritis. For the first time, we have reported that a subgroup of these patients later develop persistent synovitis with progressive asymmetric, erosive disease. The etiology of CF arthritis is unclear, but may relate to chronic infection and immune complex mechanisms. CF arthritis can be contrasted with CF induced HPO, which is associated with worse lung disease, a male predominance, and an older mean age of onset of symptoms. Mechanical neck and back pain may relate to an associated scoliosis or kyphosis in CF. |
| Databáze: | OpenAIRE |
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