Managing Disability in Progressive Multiple Sclerosis
| Autor: | Divyanshu Dubey, Peter Sguigna, Olaf Stüve |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Neurology business.industry Multiple sclerosis medicine.disease 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Sexual dysfunction Quality of life (healthcare) medicine Ocrelizumab 030212 general & internal medicine Neurology (clinical) Spasticity Cognitive decline medicine.symptom Intensive care medicine business 030217 neurology & neurosurgery Depression (differential diagnoses) medicine.drug |
| Zdroj: | Current treatment options in neurology. 18(6) |
| ISSN: | 1092-8480 |
| Popis: | Patients with progressive forms of multiple sclerosis have various symptoms which affect their quality of life significantly including depression, cognitive decline, sleep changes, bladder dysfunction, sexual dysfunction, and spasticity. Despite recent promising results on the effects of ocrelizumab on neurological disability in patients with PPMS, currently none of the immunomodulatory therapies are approved for progressive forms of multiple sclerosis. Therefore, clinicians currently mostly focus on management of well-recognized comorbidities of this disease phenotype in order to improve patients’ quality of life. There are very few studies evaluating strategies of symptomatic management on progressive forms of multiple sclerosis and most of the data is derived from studies on relapsing forms of multiple sclerosis. Understanding of the risks, benefits, and limitations of these therapies can significantly affect patient care. In this article, we review common comorbidities associated with progressive forms of multiple sclerosis and outline important strategies for their symptomatic management. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink