| Autor: |
Terence M. Williams, Theodoros N. Teknos, Mitchell Romito, Tianyun Li, Dukagjin Blakaj, Songzhu Zhao, Changxian Shen, Bhavna Kumar, Linlin Yang |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1535-7163.22505961 |
| Popis: |
Supplementary Table S1. Characteristics of study population (n=84). Supplementary Figure S1. Validation of cIAP1 antibody by immunohistochemistry. Supplementary Figure S2. Sensitivity of HNSCC cells to radiation or LCL161 as a single agent. Supplementary Figure S3. LCL161 does not alter the phosphorylation of STAT3, AKT and ERK in HNSCC cells. Supplementary Figure S4. Altered treatment schedule of LCL161 and radiation does not affect the radiosensitivity of Cal27 cells. Supplementary Figure S5. LCL161 and radiation do not substantially increase tumor cell expression of TNFα(after 24-48 hrs) but does increase TNFα secretion, and TNFα potentiates radiation mediated-apoptosis in tumor cells. Supplementary Figure S6. Kaplan-Meier survival curves demonstrating percent of mice free from tumor doubling are shown for both Cal27 and FaDu xenografts.α |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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