Correlation between climatic and biochemical parameters in etiopathogenesis of unprovoked deep vein thrombosis of the lower limbs
| Autor: | Momir Sarac, Milan Lazarević, Milan Jovanović, Dragan Milić, Zoran Damnjanović, Nemanja Stepanović |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Deep vein Early detection 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Prospective Studies Venous Thrombosis business.industry Optimal treatment Incidence General Medicine medicine.disease Thrombosis Venous thrombosis medicine.anatomical_structure Lower Extremity Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Phlebology. 36(5) |
| ISSN: | 1758-1125 |
| Popis: | Aim Beside the intention of early detection and optimal treatment of deep venous thrombosis (DVT), the aim of this study was to investigate the influence of chronobiological rhythms on the etiopathogenesis of unprovoked deep vein thrombosis of the lower limbs with monitoring of seasonal variations in biochemical parameters. Patients and methodology The prospective clinical trial included all consecutive hospitalized patients and outpatients diagnosed with DVT at the Vascular Surgery Clinic of the Clinical Center in Niš, starting from January 2013 to December 2014. Results There was no statistically significant difference in correlation between the distribution of the incidence of DVT of the lower limbs (p = 0.582), sex (p = 0.350), age (p = 0.385) and localization (p = 0.886) and the seasons. Creatinine levels were significantly higher in patients who developed DVT in spring than in those who developed DVT in winter (p Conclusion According to the results of the study, it can be concluded that in the territory of South Serbia, the seasons are not significantly related to the incidence, sex, age and localization of unprovoked DVT of the lower limbs. Creatinine levels were significantly higher in patients who developed DVT in spring than in those who developed DVT in winter, while LDL cholesterol levels were significantly higher in patients during winter than during autumn. |
| Databáze: | OpenAIRE |
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