Ecological Risk Assessment of Pharmaceuticals in the Transboundary Vecht River (Germany and The Netherlands)

Autor: Heike Schmitt, Daniel J. Duarte, Rik Oldenkamp, Jörg Klasmeier, Lucia Hernandez-Leal, Eri van Heijnsbergen, Gunnar Niebaum, Volker Lämmchen, Ad M.J. Ragas
Přispěvatelé: Global Health, RS-Research Line Resilient social-ecological systems (part of LIRSS program), RS-Research Line Learning (part of LIRSS program), Department of Environmental Sciences
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Environmental modeling
Diclofenac
010504 meteorology & atmospheric sciences
Geo-referenced modeling
Water flow
Health
Toxicology and Mutagenesis
Carbamazepine/analysis
Drainage basin
Chemical/analysis
010501 environmental sciences
01 natural sciences
Risk Assessment
Rivers
Environmental Chemistry
Animals
Humans
Water Pollutants
Ecological risk assessment
Ecosystem
0105 earth and related environmental sciences
Exposure assessment
Netherlands
geography
geography.geographical_feature_category
Water Pollutants
Chemical/analysis
Aquatic ecosystem
Water
Surface water
Geographic information systems
Carbamazepine
Water quality
Toxic effects
Water Framework Directive
Pharmaceutical Preparations
Pharmaceuticals
Environmental science
Risk assessment
Water resource management
Water Pollutants
Chemical
Environmental Sciences
Environmental Monitoring
Zdroj: Environmental toxicology and chemistry / SETAC, 41(3), 648-662. Wiley-Blackwell
Environmental Toxicology and Chemistry, 41, 3, pp. 648-662
Environmental Toxicology and Chemistry, 41, 648-662
Duarte, DJ, Niebaum, G, Lammchen, V, van Heijnsbergen, E, Oldenkamp, R, Hernandez-Leal, L, Schmitt, H, Ragas, AMJ & Klasmeier, J 2022, ' Ecological Risk Assessment of Pharmaceuticals in the Transboundary Vecht River (Germany and The Netherlands) ', Environmental Toxicology and Chemistry, vol. 41, no. 3, pp. 648-662 . https://doi.org/10.1002/etc.5062
Environmental Toxicology and Chemistry, 41(3), 648-662. John Wiley & Sons, Inc.
ISSN: 0730-7268
DOI: 10.1002/etc.5062
Popis: Millions of people rely on active pharmaceutical ingredients (APIs) to prevent and cure a wide variety of illnesses in humans and animals, which has led to a steadily increasing consumption of APIs across the globe and concurrent releases of APIs into the environment. In the environment, APIs can have a detrimental impact on wildlife, particularly aquatic wildlife. Therefore, it is essential to assess their potential adverse effects to aquatic ecosystems. The European Water Framework Directive sets out that risk assessment should be performed at the catchment level, crossing borders where needed. The present study defines ecological risk profiles for surface water concentrations of 8 APIs (carbamazepine, ciprofloxacin, cyclophosphamide, diclofenac, erythromycin, 17α-ethinylestradiol, metformin, and metoprolol) in the Vecht River, a transboundary river that crosses several German and Dutch regions. Ultimately, 3 main goals were achieved: 1) the geo-referenced estimation of API concentrations in surface water using the geography-referenced regional exposure assessment tool for European rivers; 2) the derivation of new predicted-no-effect concentrations for 7 of the studied APIs, of which 3 were lower than previously derived values; and 3) the creation of detailed spatially explicit ecological risk profiles of APIs under 2 distinct water flow scenarios. Under average flow conditions, carbamazepine, diclofenac, and 17α-ethinylestradiol were systematically estimated to surpass safe ecological concentration thresholds in at least 68% of the catchment's water volume. This increases to 98% under dry summer conditions. Environ Toxicol Chem 2022;41:648-662. © 2021 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Databáze: OpenAIRE
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