Unusual Mammalian Sex Determination Systems: A Cabinet of Curiosities
| Autor: | Frédéric Veyrunes, Paul A. Saunders |
|---|---|
| Přispěvatelé: | Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UR226, University of Tasmania [Hobart, Australia] (UTAS) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
Male Sterility sex determination [SDV.BID]Life Sciences [q-bio]/Biodiversity Review Biology QH426-470 Y chromosome 010603 evolutionary biology 01 natural sciences Evolution Molecular 03 medical and health sciences Meiosis Genetics meiosis Animals Genetics (clinical) 030304 developmental biology Mammals 0303 health sciences Sex Chromosomes Chromosome Sex Determination Processes Xy female Evolutionary biology rodents Female |
| Zdroj: | Genes Genes, MDPI, 2021, 12 (11), pp.1770. ⟨10.3390/genes12111770⟩ Genes, Vol 12, Iss 1770, p 1770 (2021) |
| ISSN: | 2073-4425 |
| Popis: | International audience; Therian mammals have among the oldest and most conserved sex-determining systems known to date. Any deviation from the standard XX/XY mammalian sex chromosome constitution usually leads to sterility or poor fertility, due to the high differentiation and specialization of the X and Y chromosomes. Nevertheless, a handful of rodents harbor so-called unusual sex-determining systems. While in some species, fertile XY females are found, some others have completely lost their Y chromosome. These atypical species have fascinated researchers for over 60 years, and constitute unique natural models for the study of fundamental processes involved in sex determination in mammals and vertebrates. In this article, we review current knowledge of these species, discuss their similarities and differences, and attempt to expose how the study of their exceptional sex-determining systems can further our understanding of general processes involved in sex chromosome and sex determination evolution. |
| Databáze: | OpenAIRE |
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