Retinoschisis Detected With Handheld Spectral-Domain Optical Coherence Tomography in Neonates With Advanced Retinopathy of Prematurity
| Autor: | Alexander C. Charonis, Thomas C. Lee, Rajeev H. Muni, Radha P. Kohly |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty genetic structures Retinoschisis medicine.medical_treatment Gestational Age Diagnostic Techniques Ophthalmological Ophthalmology Intensive care medicine Humans Retinopathy of Prematurity Fluorescein Angiography Retrospective Studies Laser Coagulation medicine.diagnostic_test business.industry Infant Newborn Fundus photography Retinal detachment Retinopathy of prematurity medicine.disease Fluorescein angiography eye diseases Infant Extremely Low Birth Weight Disease Progression sense organs business Laser coagulation Tomography Optical Coherence Retinopathy |
| Zdroj: | Archives of Ophthalmology. 128:57 |
| ISSN: | 0003-9950 |
| DOI: | 10.1001/archophthalmol.2009.361 |
| Popis: | Objectives The recent development of handheld spectral-domain optical coherence tomography (HHSD-OCT) has enabled us to obtain high-resolution retinal scans of premature infants with retinopathy of prematurity (ROP). The purpose of this study is to document HHSD-OCT findings in laser-treated neonates with progressive ROP. Methods This is a retrospective consecutive case series of 3 patients with progressive ROP despite laser photocoagulation. All patients were transferred from peripheral neonatal intensive care units (NICUs) to the Children's Hospital Los Angeles. All patients had a complete ocular examination, fundus photography, fluorescein angiography, and HHSD-OCT. Results All 3 patients had active progressive ROP despite prior laser photocoagulation. Of the 6 eyes, 1 was excluded from the study because it had an exudative retinal detachment following laser photocoagulation. Retinal detachment was not detected on clinical examination in the 5 remaining eyes, although there was vitreoretinal traction at the ridges of 3 of the 5 eyes. The HHSD-OCT identified presumed retinoschisis in all 5 study eyes. Conclusions Tractional retinoschisis may be an important finding in progressive laser-treated ROP, made possible by use of the HHSD-OCT. This finding may have significant implications for how we classify and treat patients whose ROP is progressing despite laser treatment. Furthermore, the use of the HHSD-OCT can provide valuable insight into the interaction of the retina, vitreous, and ridge in patients with progressive ROP, and it allows shallow detachments and retinoschisis to be diagnosed earlier and more accurately than would otherwise be possible. |
| Databáze: | OpenAIRE |
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