Pathological interactions with the timing of birth and uterine activation
Autor: | Roger Smith, Dirk F. van Helden, M.A. Read, Helena C. Parkington, Eng-Cheng Chan, Dimitris K. Grammatopoulos, Jonathon J Hirst, Hannah K. Palliser, Richard C. Nicholson, Tamas Zakar |
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Rok vydání: | 2007 |
Předmět: |
medicine.medical_specialty
Labor Obstetric Corticotropin-Releasing Hormone Obstetrics business.industry Preterm labour Parturition Obstetrics and Gynecology Cervix Uteri General Medicine Bioinformatics Uterine Contraction Tocolytic Agents Corollary Pregnancy Myometrium medicine Humans Premature Birth Female business Pathological |
Zdroj: | The Australian and New Zealand Journal of Obstetrics and Gynaecology. 47:430-437 |
ISSN: | 1479-828X 0004-8666 |
Popis: | The physiological processes that regulate the onset of parturition and birth are slowly being elucidated, and the points at which pathology can intervene are becoming more apparent. The data support the view that multiple pathways lead to myometrial activation. The clinical corollary is that combinations of tocolytics that operate via different mechanisms may be more effective than single agents. It may also be necessary to divide preterm labour into groups based on underlying mechanisms and to tailor therapy accordingly. |
Databáze: | OpenAIRE |
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