Reduced Survival in Patients with 'Coronary Microvascular Disease'
Autor: | Ramdas G. Pai, Padmini Varadarajan, Shuja Rasool, Stephen Rechenmacher, Terence Lin |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: |
medicine.medical_specialty
education.field_of_study business.industry Population medicine.disease Chest pain Article Pulse pressure Coronary artery disease Stenosis Blood pressure medicine.anatomical_structure Internal medicine Cohort medicine Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business education Artery |
Popis: | The syndrome of chest pain, abnormal stress test, and nonflow limiting coronary artery disease (CAD) is common and is attributed to coronary microvascular disease (µVD). It is associated with increased hospital admissions and health care costs. But its impact on long-term survival is not known. Of the 9941 consecutive patients who had an exercise stress test for evaluation of chest pain between May 1991 and July 2007, 935 had both a positive stress test and a coronary angiogram within 1 year of their stress test forming the study cohort. Significant angiographic CAD defined as ≥70% stenosis of an epicardial coronary artery or ≥50% stenosis of the left main coronary artery was present in 324 patients. Rest (n = 611) were considered to have coronary µVD. Compared with patients with significant epicardial CAD, patients with coronary µVD were younger (63 ± 11 vs. 65 ± 10 years, p = 0.002), and had lower left ventricular wall thickness (p |
Databáze: | OpenAIRE |
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