Serotypes of Streptococcus pneumoniae isolated from blood and cerebrospinal fluid related to vaccine serotypes and to clinical characteristics

Autor:	Lars Jonsson, Margit S. Kaltoft, Helle Bossen Konradsen, Berndt E. B. Claesson, Elisabeth Ek, Elisabet Persson, Stefan Berg, Siv Johansson, Erik Backhaus, Peter Larsson, Torvald Ripa, Gunilla Rådberg, Birger Trollfors
Rok vydání:	2006
Předmět:	Microbiology (medical) Serotype Adult Male Adolescent medicine.disease_cause Polysaccharide Vaccine Pneumococcal Infections Microbiology Cerebrospinal fluid Streptococcus pneumoniae medicine Humans Mortality Serotyping Mortality trends Child Aged Aged 80 and over Vaccines Conjugate General Immunology and Microbiology business.industry Streptococcal Vaccines Infant Newborn Infant General Medicine Middle Aged Virology Infectious Diseases Child Preschool Female business
Zdroj:	Scandinavian journal of infectious diseases. 38(6-7)
ISSN:	0036-5548
Popis:	Pneumococci isolated from blood and cerebrospinal fluid from 1998 to 2001 in 2 counties in south-west Sweden were serotyped with the capsular reaction test. Of the 836 strains, 353 (42%), 598 (72%) and 789 (94%) belonged to serotypes included in the 7- and 11-valent pneumococcal conjugate vaccines and in the 23-valent polysaccharide vaccine, respectively. The most common serotype was type 1 (119 isolates) followed in descending frequency by serotypes 7F, 9V, 14, 4 and 12F (90-49 isolates per serotype). The coverage rates of the 7- and 11-valent conjugate vaccines among 58 strains isolated from children and adolescents 0-19 y of age were 46% and 93%, respectively. A comparison of clinical characteristics of infections caused by different serotypes showed that types 1 and 7F were less commonly associated with severe underlying diseases, that patients infected with these serotypes were younger than the average and, thus, had a lower case-fatality rate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190e11a9229e1c880da5d87505a8d0a7 https://pubmed.ncbi.nlm.nih.gov/16798688 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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