Phase Transitions in Dipalmitoylphosphatidylcholine Monolayers
| Autor: | Jinlong Yang, A. Wilhelm Neumann, Rimei Chen, Xianju Wang, Yi Y. Zuo, Z. Policova |
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| Rok vydání: | 2016 |
| Předmět: |
Phase transition
Langmuir Analytical chemistry 02 engineering and technology 010402 general chemistry 01 natural sciences Article chemistry.chemical_compound Polymorphism (biophysics) Monolayer Electrochemistry General Materials Science Soft matter Spectroscopy Drop (liquid) technology industry and agriculture Surfaces and Interfaces 021001 nanoscience & nanotechnology Condensed Matter Physics 0104 chemical sciences chemistry Chemical physics Dipalmitoylphosphatidylcholine lipids (amino acids peptides and proteins) 0210 nano-technology Membrane biophysics |
| Zdroj: | Langmuir : the ACS journal of surfaces and colloids. 32(33) |
| ISSN: | 1520-5827 |
| Popis: | A self-assembled phospholipid monolayer at an air–water interface is a well-defined model system for studying surface thermodynamics, membrane biophysics, thin-film materials, and colloidal soft matter. Here we report a study of two-dimensional phase transitions in the dipalmitoylphosphatidylcholine (DPPC) monolayer at the air–water interface using a newly developed methodology called constrained drop surfactometry (CDS). CDS is superior to the classical Langmuir balance in its capacity for rigorous temperature control and leak-proof environments, thus making it an ideal alternative to the Langmuir balance for studying lipid polymorphism. In addition, we have developed a novel Langmuir–Blodgett (LB) transfer technique that allows the direct transfer of lipid monolayers from the droplet surface under well-controlled conditions. This LB transfer technique permits the direct visualization of phase coexistence in the DPPC monolayer. With these technological advances, we found that the two-dimensional phase behavior of the DPPC monolayer is analogous to the three-dimensional phase transition of a pure substance. This study has implications in the fundamental understanding of surface thermodynamics as well as applications such as self-assembled monolayers and pulmonary surfactant biophysics. |
| Databáze: | OpenAIRE |
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